With regard to the following article: D. Kaya, A. Dinçer, M.E. Yildiz, M.O. Çizmeli, and C. Erzen Acute Ischemic Infarction Defined by a Region of Multiple Hypointense Vessels on Gradient-Echo T2* MR Imaging at 3T
AJNR Am J Neuroradiol first published on April 3, 2009 as doi: 10.3174/ajnr.A1537; kudos to the authors for investigating an important topic – that of unenhanced acute stroke imaging.  Given the recent concern with NSF, it is more important than ever to continue to develop unenhanced MRI methods for diagnosing infarct core and penumbra, such as ASL.