A 39-year-old man with history of tingling sensation on the left half of Face.
MRI revealed a solitary lesion in the splenium of the corpus callosum, hyperintense on T2/FLAIR and hypointense on T1W images. There is diffusion restriction.
This lesion was presumed demyelinating in view of h/o upper respiratory tract infection. At 6-week follow up MRI the lesion resolved completely.
Various etiologies have been reported for transient splenial lesions like:
- Seizures
- Sudden withdrawal of antiepileptic drugs
- Brain infarction
- Multiple sclerosis
- Cerebral trauma
- Neoplasm
- Adrenoleukodystrophy
- AIDS dementia complex
- Infections like influenza, measles, herpes, Salmonella, mumps, adenovirus, varicella zoster, Legionnaires disease, rotavirus, HIV, tubercular meningitis
- Hypoglycemia
- Marchiafava-Bignami syndrome
- Hemolytic-uremic syndrome with encephalopathy
In absence of significant history of any of these conditions, how do we report this lesion and how often follow it up with MR?
How to report Transient Splenial Lesion and How Often to Follow It Up?