Fellows’ Journal Club
December 2014
(3 of 3)
Three different techniques were used to assess extracranial carotid artery stenosis and correlated with the results of DSA: conventional TOF MRA, black-blood MRA, and CTA. There was good correlation among all 4 techniques with CTA having the highest sensitivity/specificity followed by black-blood MRA. CTA and black-blood MRA were also better for depicting plaque features.
Abstract
BACKGROUND AND PURPOSE
Dual-source CTA and black-blood MRA are recently developed techniques for evaluating carotid stenosis. The purpose of this study was to compare dual-source CTA with black-blood MRA and conventional TOF MRA in both detecting carotid stenosis by using DSA as a reference standard and demonstrating plaque morphology.
MATERIALS AND METHODS
Thirty patients with suspected carotid artery stenosis underwent unenhanced MRA by using black-blood and TOF MRA and dual-source CTA. Source images from unenhanced MRAs and dual-source CTA were reconstructed with MIP or curved planar reconstruction. The degree of carotid artery stenosis was measured, and plaque surface morphology at the stenosis was analyzed and compared among different techniques.
RESULTS
Good correlation was observed for measuring the degree of carotid stenosis among dual-source CTA, black-blood MRA, TOF MRA, and DSA. Sensitivity and specificity for detecting severe stenosis were 100% and 97% with dual-source CTA, 100% and 95% with black-blood MRA, and 79% and 95% with TOF MRA. None of the 3 technologies resulted in stenosis of <50% being overestimated. Plaque surface irregularity or ulceration was more frequently detected with dual-source CTA and black-blood MRA than with TOF MRA and DSA.
CONCLUSIONS
This preliminary study shows that black-blood MRA is a promising technique, comparable with dual-source CTA and DSA, but better than TOF MRA, in the evaluation of carotid stenosis. Unlike dual-source CTA, black-blood MRA requires no intravenous contrast or radiation.
