Fellows’ Journal Club Choices for April 2015

Shams S, Martola J, Granberg T, et al. Cerebral Microbleeds: Different Prevalence, Topography, and Risk Factors Depending on Dementia Diagnosis — The Karolinska Imaging Dementia Study. http://www.ajnr.org/content/36/4/661.full

MR studies in more than 1500 patients with dementia revealed that 22% had microbleedsthat were predominantly lobar and occipital in cases of Alzheimer disease. Patients with microbleeds were older, male, and hypertensive. Prevalence, location, and risk factors of microbleeds varied depending on dementia diagnosis and may be taken into account when anticoagulating such patients.

Bertrand A, Vignal C, Lafitte F, et al. Open-Angle Glaucoma and Paraoptic Cyst: First Description of a Series of 11 Patients. http://www.ajnr.org/content/36/4/779.full

MR imaging in 11 patients with severe glaucoma and paraoptic cysts is reported. The cysts showed high T2 and variable T1 signal. The authors suggest that these cysts work as valves and may serve to preserve vision.

Polan RM, Poretti A, Huisman TAGM, et al. Susceptibility-Weighted Imaging in Pediatric Arterial Ischemic Stroke: A Valuable Alternative for the Noninvasive Evaluation of Altered Cerebral Hemodynamics. http://www.ajnr.org/content/36/4/783.full

Based on imaging findings in 24 pediatric patients,the authors conclude that SWI-DTI mismatch predicts progression in pediatric arterial ischemic stroke. SWI-hyperintense signal is not useful for predicting the development of malignant edemabut SWI should be routinely added to the neuroimaging diagnostic protocol of pediatric arterial ischemic stroke.

Fellows’ Journal Club Choices for April 2015
Mauricio Castillo
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