Fellows’ Journal Club The authors evaluated the diagnostic performance of a machine-learning algorithm by using texture analysis of contrast-enhanced T1-weighted images for differentiation of primary central nervous system lymphoma (n=35) and enhancing glioma (n=71). The mean areas under the receiver
Editor’s Choice The authors characterized the susceptibility mapping of cortical lesions in patients with MS (n=36) and compared it with neuropathologic observations (n=16). Neuropathologic analysis revealed the presence of an intense band of microglia activation close to the pial membrane
Fellows’ Journal Club The authors retrospectively reviewed a consecutive series of patients with diffuse intracranial dolichoectasia and compared demographics, vascular risk factors, additional aneurysm prevalence, and clinical outcomes with a group of patients with vertebrobasilar dolichoectasia. Twenty-five patients had diffuse
Fellows’ Journal Club The authors used CTA to assess arterial stenosis and occlusion in an ischemic stroke population arriving at a tertiary stroke center within 24 hours of symptom onset to obtain a comprehensive picture of occlusive disease pattern. Extra-
Editor’s Choice Ninety-one localized biopsies were obtained from 36 patients with glioblastoma. Signal intensities corresponding to these samples were derived from T1-postcontrast subtraction, T2-FLAIR, and ADC sequences by using an automated coregistration algorithm. Cell density was calculated for each specimen
Editor’s Choice Super selective pseudocontinuous arterial spin-labeling with a circular labeling spot enabling selective vessel labeling was added to routine imaging in a prospective pilot study in 50 patients with extracranial steno-occlusive disease. The detected vessel occlusions/stenoses and perfusion patterns
Fellows’ Journal Club The authors wanted to determine whether imaging characteristics previously associated with oligodendroglial tumors were still applicable given the 2016 WHO classification that made IDH mutation and 1p/19q codeletion the defining features of oligodendroglioma. They found that 92%
Editor’s Choice Fourteen patients with tumefactive demyelinating lesions and 21 patients with high-grade gliomas underwent MR imaging with conventional, DTI, and DSC perfusion imaging. Conventional imaging sequences had a sensitivity of 80.9% and specificity of 57.1% in differentiating high-grade gliomas
Fellows’ Journal Club MR fingerprinting is a technique in which pseudorandomized acquisition parameters are used to simultaneously quantify multiple tissue properties, including T1 and T2 relaxation times. The authors evaluated the ability of MR fingerprinting–derived T1 and T2 relaxometry to
Editor’s Choice The authors assessed the prognostic efficacy of individual-versus-combined regional volumetrics in 2 commercially available brain volumetric software packages for predicting conversion of patients with mild cognitive impairment to Alzheimer disease. One hundred ninety-two subjects (mean age, 74.8 years)
