Comparison of Quantitative Cerebral Blood Flow Measurements Performed by Bookend Dynamic Susceptibility Contrast and Arterial Spin-Labeling MRI in Relapsing-Remitting Multiple Sclerosis

Jeffrey Ross December 24, 2016December 19, 2016 Brain, Editor's Choices

Editor’s Choice Both dynamic susceptibility contrast perfusion with bookend T1-calibration and pseudocontinuous arterial spin-labeling have been used recently for CBF quantification in relapsing-remitting MS. The authors compared pseudocontinuous arterial spin-labeling CBF with the bookend technique in a prospective cohort of

Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma

Jeffrey Ross December 17, 2016December 16, 2016 Brain, Editor's Choices

Editor’s Choice The authors explored regions of diffusion restriction following bevacizumab therapy in patients with glioblastoma by 1) analyzing tissue samples from patients at postmortem to pathologically confirm tumor cellularity or coagulative necrosis and 2) assessing the patient populationto determine

Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores: Recanalization Rates, Periprocedural Complications, and Clinical Outcome

Jeffrey Ross December 3, 2016December 2, 2016 Editor's Choices, Interventional

Editor’s Choice This is a retrospective analysis of 484 patients in a prospectively collected stroke data base. The inclusion criteria were anterior circulation ischemic stroke treated with mechanical thrombectomy at a single institution between September 2010 and October 2015 with

Comparison of CTA- and DSA-Based Collateral Flow Assessment in Patients with Anterior Circulation Stroke

Jeffrey Ross November 26, 2016November 22, 2016 Brain, Editor's Choices

Editor’s Choice The authors set out to determine the agreement between collateral flow assessment on CTA and DSA and their respective associations with clinical outcome. They used patient data that was randomized in MR CLEAN with middle cerebral artery occlusion

Early Biomarkers from Conventional and Delayed-Contrast MRI to Predict the Response to Bevacizumab in Recurrent High-Grade Gliomas

Jeffrey Ross November 19, 2016November 18, 2016 Brain, Editor's Choices

Editor’s Choice Twenty-four patients with recurrent high-grade gliomas were scanned before and during bevacizumab treatment with standard and delayed-contrast MRI. The mean change in lesion volumes of responders (overall survival, >1 year) and nonresponders (overall survival, <1 year) was evaluated.

Imaging Appearance of SMARCB1 (INI1)-Deficient Sinonasal Carcinoma: A Newly Described Sinonasal Malignancy

Jeffrey Ross November 5, 2016November 4, 2016 Editor's Choices, Head and Neck

Editor’s Choice SMARCB1 (INI1) is a tumor-suppressor gene that has been implicated in a growing number of malignancies involving multiple anatomic sites, including the kidneys, soft tissues, and the CNS (See OMIM *601607). The authors describe a case series of

Ocular Signs Caused by Dural Arteriovenous Fistula without Involvement of the Cavernous Sinus: A Case Series with Review of the Literature

Jeffrey Ross October 29, 2016November 4, 2016 Editor's Choices, Interventional

Editor’s Choice Ocular signs are unusual in the presentation of cranial dural arteriovenous fistulas in locations other than the cavernous sinus. Between 2000–2015, 13 patients met the inclusion criteria for this retrospective analysis. The most common signs were chemosis (61.5%),

Magnetic Susceptibility from Quantitative Susceptibility Mapping Can Differentiate New Enhancing from Nonenhancing Multiple Sclerosis Lesions without Gadolinium Injection

Jeffrey Ross October 22, 2016October 21, 2016 Brain, Editor's Choices

Editor’s Choice In 54 patients, new T2-weighted lesions were evaluated for enhancement on conventional T1-weighted imaging with gadolinium, and their susceptibility values were measured on quantitative susceptibility mapping. Eighty-six of 133 new lesions that were gadolinium-enhancing had relative susceptibility values

Risk Factors for Ischemic Complications following Pipeline Embolization Device Treatment of Intracranial Aneurysms: Results from the IntrePED Study

Jeffrey Ross October 1, 2016September 30, 2016 Editor's Choices, Interventional

Editor’s Choice This is a retrospective subanalysis of the IntrePED study, which has beenpreviously published (AJNR Am J Neuroradiol 2015;36:108–15).Seven hundred ninety-three patients with 906 treated aneurysms were enrolled. Thirty-six (4.5%) patients had postoperative acute ischemic stroke, 21 of which

Quantitative Susceptibility Mapping and R2* Measured Changes during White Matter Lesion Development in Multiple Sclerosis: Myelin Breakdown, Myelin Debris Degradation and Removal, and Iron Accumulation

Jeffrey Ross September 24, 2016September 23, 2016 Brain, Editor's Choices

Editor’s Choice The authors characterized lesion changes on quantitative susceptibility mapping and R2* at various gadolinium enhancement stages (nodular, shell-like, nonenhancing) in 64 patients with 203 lesions. They found that: 1) active MS lesions with nodular enhancement show R2* decrease

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