Editor’s Choice DSC-MR imaging using preload, intermediate (60°) flip angle and postprocessing leakage correction has gained traction as a standard methodology. Simulations suggest that DSC-MR imaging with flip angle = 30° and no preload yields relative CBV practically equivalent to
1. Solomon AJ, Naismith RT, Cross AH. Misdiagnosis of multiple sclerosis. Neurology. 2019;92(1):26-33. doi:10.1212/WNL.0000000000006583. The expert panel that formulated the 2017 McDonald criteria acknowledged that the current criteria “were not developed to differentiate MS from other conditions” but rather to
Fellows’ Journal Club In this technical report, the authors used MR myelography to demonstrate the feasibility of T1 mapping to quantify contrast concentration to analyze glymphatic flow in man. There is increasing interest in its use as a biomarker and
Editor’s Choice The authors analyzed the accuracy of gadolinium SWI for detecting the imaging evidence of active inflammation on MS plaques when a BBB dysfunction was demonstrated by a focal gadolinium-enhanced lesion and compared this technique with gadolinium-enhanced T1 spin-echo
1. Fox MD. Mapping Symptoms to Brain Networks with the Human Connectome. N Engl J Med. 2018;379(23):2237-2245. doi:10.1056/NEJMra1706158. Single-lesion analysis has been the foundation of clinical neurology and the basis for localization of most neurologic symptoms and behaviors. The traditional
Fellows’ Journal Club The authors evaluated tumor cell density using a transfer learning method that generates individualized patient models, grounded in the wealth of population data, while also detecting and adjusting for interpatient variabilities based on each patient’s own histologic
Editor’s Choice The authors applied an optimized TSE T2 sequence to washed postmortem brain samples to reveal exquisite and reproducible brain stem anatomic MR imaging contrast comparable with histologic atlases. Direct TSE MR imaging sequence discrimination of brain stem anatomy
Fellows’ Journal Club One hundred two IDH-mutant lower grade gliomas with preoperative MR imaging and known 1p/19q status from The Cancer Genome Atlas composed a training dataset. Two neuroradiologists in consensus analyzed the training dataset for various imaging features: tumor
1. Gallina P, Lastrucci G, Caini S, Lorenzo N Di, Porfirio B, Scollato A. Accuracy and safety of 1-day external lumbar drainage of CSF for shunt selection in patients with idiopathic normal pressure hydrocephalus. J Neurosurg. 2018:1-7. doi:10.3171/2018.6.JNS18400. Cerebrospinal fluid
Fellows’ Journal Club Of 101 included patients, the 4 subgroups of >6 were the following: chemotherapy (n = 35), opiates (n = 19), acute hepatic encephalopathy (n = 14), and immunosuppressants (n = 11). Other causes (n = 22 total)
